Name: Acetadote

Commonly used brand name(s)

In the U.S.

  • Acetadote

Available Dosage Forms:

  • Solution

Therapeutic Class: Acetaminophen Antidote

Chemical Class: Amino Acid

Uses For Acetadote

Acetylcysteine injection is used to help prevent or lessen liver damage caused by an overdose of acetaminophen.

This medicine is to be given only by or under the direct supervision of your doctor.

What do I need to tell my doctor BEFORE I take Acetadote?

  • If you have an allergy to acetylcysteine or any other part of Acetadote (acetylcysteine injection).
  • If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.

This medicine may interact with other drugs or health problems.

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this medicine with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

Acetadote Overview

Acetadote is a brand name medication included in the following groups of medications: Antidotes, Mucolytics, OTHER OPHTHALMOLOGICALS. For more information about Acetadote see its generic Acetylcysteine

Acetylcysteine Pregnancy Warnings

Animal studies did not show teratogenicity; slightly decreased fertility was seen at doses above the maximum human dose. Limited case reports did not report any adverse fetal or neonatal outcomes. This drug crosses the placenta and was measurable in the serum of the infant. A 1999 report concluded that pregnant women should be managed the same way as nonpregnant patients for acetaminophen overdose, and that acetylcysteine therapy was protective to both mother and fetus. There are no controlled data in human pregnancy

Use is not recommended unless clearly needed. AU TGA pregnancy category: B2 US FDA pregnancy category: B

Acetylcysteine Breastfeeding Warnings

Animal studies did not show adverse effects during lactation. It is unknown in this drug or its metabolites are excreted in milk. Based on the pharmacokinetics, it should be nearly cleared 30 hours after administration.

Use is not recommended. Excreted into human milk: Unknown Excreted into animal milk: Data not available Comments: May consider resuming nursing 30 hours after the last administration.