Acetaminophen and guaifenesin

Name: Acetaminophen and guaifenesin

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

The first signs of an acetaminophen overdose include loss of appetite, nausea, vomiting, stomach pain, sweating, and confusion or weakness. Later symptoms may include pain in your upper stomach, dark urine, and yellowing of your skin or the whites of your eyes.

Acetaminophen and guaifenesin dosing information

Usual Adult Dose for Cough:

Acetaminophen-guaifenesin 325 mg-200 mg oral tablet:
2 tablets orally every 4 to 6 hours not to exceed 12 tablets daily.

Acetaminophen-guaifenesin 500 mg-200 mg/15 mL oral liquid:
30 mL orally every 4 to 6 hours not to exceed 120 mL per day.

Acetaminophen-guaifenesin 1000 mg-400 mg oral powder for reconstitution:
1 packet orally every 6 hours not to exceed 4 packets in 24 hours.

Usual Adult Dose for Pain:

Acetaminophen-guaifenesin 325 mg-200 mg oral tablet:
2 tablets orally every 4 to 6 hours not to exceed 12 tablets daily.

Acetaminophen-guaifenesin 500 mg-200 mg/15 mL oral liquid:
30 mL orally every 4 to 6 hours not to exceed 120 mL per day.

Acetaminophen-guaifenesin 1000 mg-400 mg oral powder for reconstitution:
1 packet orally every 6 hours not to exceed 4 packets in 24 hours.

Usual Adult Dose for Headache:

Acetaminophen-guaifenesin 325 mg-200 mg oral tablet:
2 tablets orally every 4 to 6 hours not to exceed 12 tablets daily.

Acetaminophen-guaifenesin 500 mg-200 mg/15 mL oral liquid:
30 mL orally every 4 to 6 hours not to exceed 120 mL per day.

Acetaminophen-guaifenesin 1000 mg-400 mg oral powder for reconstitution:
1 packet orally every 6 hours not to exceed 4 packets in 24 hours.

Usual Pediatric Dose for Cough:

Acetaminophen-guaifenesin 325 mg-200 mg oral tablet
12 yrs or older: 2 tablets orally every 4 to 6 hours not to exceed 12 tablets daily.

Acetaminophen-guaifenesin 1000 mg-400 mg oral powder for reconstitution:
12 yrs or older: 1 packet orally every 6 hours not to exceed 4 packets in 24 hours.

Usual Pediatric Dose for Pain:

Acetaminophen-guaifenesin 325 mg-200 mg oral tablet
12 yrs or older: 2 tablets orally every 4 to 6 hours not to exceed 12 tablets daily.

Acetaminophen-guaifenesin 1000 mg-400 mg oral powder for reconstitution:
12 yrs or older: 1 packet orally every 6 hours not to exceed 4 packets in 24 hours.

Usual Pediatric Dose for Headache:

Acetaminophen-guaifenesin 325 mg-200 mg oral tablet
12 yrs or older: 2 tablets orally every 4 to 6 hours not to exceed 12 tablets daily.

Acetaminophen-guaifenesin 1000 mg-400 mg oral powder for reconstitution:
12 yrs or older: 1 packet orally every 6 hours not to exceed 4 packets in 24 hours.

Usual Adult Dose for Cough

Acetaminophen-guaifenesin 325 mg-200 mg oral tablet:
2 tablets orally every 4 to 6 hours not to exceed 12 tablets daily.

Acetaminophen-guaifenesin 500 mg-200 mg/15 mL oral liquid:
30 mL orally every 4 to 6 hours not to exceed 120 mL per day.

Acetaminophen-guaifenesin 1000 mg-400 mg oral powder for reconstitution:
1 packet orally every 6 hours not to exceed 4 packets in 24 hours.

Usual Pediatric Dose for Pain

Acetaminophen-guaifenesin 325 mg-200 mg oral tablet
12 yrs or older: 2 tablets orally every 4 to 6 hours not to exceed 12 tablets daily.

Acetaminophen-guaifenesin 1000 mg-400 mg oral powder for reconstitution:
12 yrs or older: 1 packet orally every 6 hours not to exceed 4 packets in 24 hours.

Acetaminophen / guaifenesin Breastfeeding Warnings

Acetaminophen is excreted into human milk in small concentrations. One case of a rash has been reported in a nursing infant. Acetaminophen is considered compatible with breast-feeding by the American Academy of Pediatrics. There are no data on the excretion of guaifenesin into human milk. The manufacturer recommends that due to the potential for serious adverse reactions in nursing infants, a decision should be made to discontinue nursing or discontinue the drug, taking into account the importance of the drug to the mother.

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