Active FE

Name: Active FE

Active FE - Clinical Pharmacology

Iron is an essential component in the formation of hemoglobin. Adequate amounts of iron are necessary for effective erythropoiesis. Iron also serves as a cofactor of several essential enzymes, including cytochromes that are involved in electron transport. Folic acid is required for nucleoprotein synthesis and the maintenance of normal erythropoiesis. Folic acid is converted in the liver and plasma to its metabolically active form, tetrahydrofolic acid, by dihydrofolate reductase. Vitamin B12 is required for the maintenance of normal erythropoiesis, nucleoprotein and myelin synthesis, cell reproduction and normal growth. Intrinsic factor, a glycoprotein secreted by the gastric mucosa, is required for active absorption of vitamin B12 from the gastrointestinal tract.

Indications and Usage for Active FE

Active FE™ is indicated for the prevention and treatment of iron deficiency anemia and/or nutritional megaloblastic anemias.1

1 This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent disease.

For the Consumer

Applies to multivitamin with iron: oral capsule, oral miscellaneous, oral solution reconstituted, oral tablet, oral tablet extended release

Other dosage forms:

  • oral powder, oral tablet chewable
  • oral capsule, oral elixir, oral liquid, oral miscellaneous, oral solution, oral tablet
  • oral liquid, oral solution, oral suspension

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Black, tarry, or bloody stools.
  • Fever.
  • Very upset stomach or throwing up.
  • Very bad belly pain.
  • Throwing up blood or throw up that looks like coffee grounds.
  • Stomach cramps.

Usual Adult Dose for Vitamin/Mineral Supplementation

Antioxidant Multiple Vitamins (A,D,E,K-intensive) and Minerals oral capsule:
2 capsules orally once daily.

Calcium, Magnesium and Phosphorus oral tablet:
2 tablets orally 3 times per day.

Calcium with Vitamin D and K oral tablet:
1 tablet orally twice daily.

Multiple Vitamins with Zinc oral capsule:
2 capsules orally once daily.

Therapeutic Multiple Vitamins with Minerals oral tablet, chewable:
1 tablet chewed daily with food.

Vitamin B Complex with C and Calcium oral tablet:
3 tablets orally daily preferably after a meal.

Vitamin B Complex with C, Folic Acid, Iron and Zinc oral tablet:
1 tablet orally once daily.

Vitamin B Complex with D, Calcium and Folic Acid oral wafer:
1 wafer chewed twice daily.

Vitamin B Complex with Folic Acid and Minerals oral tablet:
1 to 2 tablets orally once or twice daily.

Renal Dose Adjustments

Patients with impaired kidney function should not take magnesium supplements without physician supervision.