Asthmanefrin

Name: Asthmanefrin

Asthmanefrin Interactions

Avoid getting this medicine in your eyes.

Avoid eating or drinking products that contain caffeine, such as coffee, tea, soft drinks, or energy drinks. Taking caffeine while you are using racepinephrine can increase your blood pressure.

Tell your doctor about all your current medicines and any you start or stop using, especially:

  • other asthma medications;
  • diet pills, an appetite suppressant, or stimulant medicine;
  • cold or allergy medicine that contains a decongestant; or
  • an antidepressant or medicine to treat mental illness.

This list is not complete. Other drugs may interact with racepinephrine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

Pregnancy & Lactation

Pregnancy Category: C

Lactation: Excreted in breast milk

Pregnancy Categories

A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA:Information not available.

What happens if I miss a dose?

Since racepinephrine is used when needed, you may not be on a dosing schedule. If you are on a schedule, use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

Do not use more than 12 inhalations of racepinephrine in a 24-hour period.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What other drugs will affect Asthmanefrin (racepinephrine)?

Tell your doctor about all your current medicines and any you start or stop using, especially:

  • other asthma medications;

  • diet pills, an appetite suppressant, or stimulant medicine;

  • cold or allergy medicine that contains a decongestant; or

  • an antidepressant or medicine to treat mental illness.

This list is not complete. Other drugs may interact with racepinephrine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

For the Consumer

Applies to racepinephrine: inhalation solution

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • new or worsening asthma symptoms;

  • fast heart rate, tremors or a nervous feeling;

  • sleep problems (insomnia);

  • a seizure (convulsions); or

  • dangerously high blood pressure--severe headache, blurred vision, pounding in your neck or ears, nosebleed, anxiety, confusion, severe chest pain, shortness of breath, irregular heartbeats.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to racepinephrine: inhalation solution

Cardiovascular

Cardiovascular side effects have included elevations of heart rate and blood pressure. In smaller doses, racepinephrine (the active ingredient contained in Asthmanefrin) has caused peripheral coronary arterial vasodilation, but in larger doses, racepinephrine has caused diffuse vasoconstriction. This has caused increased peripheral vascular resistance, which was important in patients with coronary artery disease (worsened myocardial ischemia/angina) or hypertension (risk of emergent hypertension/stroke).

Arrhythmias, including fatal ventricular fibrillation, have been reported in patients with underlying cardiac disease. Rapid rises in blood pressure have produced cerebral hemorrhage, particularly in elderly patients with cardiovascular disease. Angina may occur in patients with coronary artery disease.[Ref]

Gastrointestinal

Gastrointestinal side effects have included nausea and vomiting.[Ref]

Nervous system

Nervous system side effects have included fear, agitation, anxiety, tenseness, restlessness, headache, tremor, dizziness, lightheadedness, nervousness, sleeplessness, excitability, weakness, and increased parkinsonian tremors.[Ref]

Psychiatric

Psychiatric side effects have included agitation, disorientation, impaired memory, aggressive or assautive behavior, hallucinations, and psychosis.

Some side effects of Asthmanefrin may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Renal Dose Adjustments

Data not available

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