Campral

Name: Campral

Brand names

  • Campral®

Campral and Pregnancy

Tell your doctor if you are pregnant or plan to become pregnant.

The FDA categorizes medications based on safety for use during pregnancy. Five categories - A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy.

Campral falls into category C. In animal studies, pregnant animals were given this medication and had some babies born with problems. No well-controlled studies have been done in humans. Therefore, this medication may be used if the potential benefits to the mother outweigh the potential risks to the unborn child.

Other Requirements

  • Store Campral at 25ºC (77ºF).
  • Keep this and all medicines out of the reach of children.

Interactions for Campral

Does not induce CYP isoenzymes 1A2 or 3A4; does not inhibit CYP isoenzymes 1A2, 2C9, 2C19, 2D6, 2E1, or 3A4.1

Concomitant use with anxiolytics, hypnotics and sedatives (including benzodiazepines), or nonopiate analgesics not associated with changes in safety profile.1

Specific Drugs

Drug

Interaction

Comments

Alcohol

Pharmacokinetic interaction unlikely1

Antidepressants

Antidepressants: Changes in weight (i.e., loss or gain) reported 1

Desipramine: No change in pharmacokinetics of the antidepressant1

Imipramine: No change in pharmacokinetics of the antidepressant1

Diazepam

Pharmacokinetic interaction unlikely1

Disulfiram

Pharmacokinetic interaction unlikely1

Naltrexone

Increased concentrations of acamprosate; no change in concentrations of naltrexone or its major metabolite, 6-β-naltrexol1

No dosage adjustment recommended1

Commonly used brand name(s)

In the U.S.

  • Campral

Available Dosage Forms:

  • Tablet, Delayed Release
  • Tablet, Enteric Coated

Therapeutic Class: Ethanol Dependency

Uses of Campral

  • It is used to help keep you alcohol-free.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Patients who take Campral may be at a greater risk of having thoughts or actions of suicide. The risk may be greater in people who have had these thoughts or actions in the past. Call the doctor right away if signs like low mood (depression), nervousness, restlessness, grouchiness, panic attacks, or changes in mood or actions are new or worse. Call the doctor right away if any thoughts or actions of suicide occur.

Consumer Information Use and Disclaimer

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else's drugs.
  • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
  • Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
  • Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about this medicine, please talk with your doctor, nurse, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

This information should not be used to decide whether or not to take Campral or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Campral. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine.

Review Date: October 4, 2017

Contraindications

Hypersensitivity to Acamprosate Calcium

Campral is contraindicated in patients who previously have exhibited hypersensitivity to acamprosate calcium or any of its components.

Severe Renal Impairment

Campral is contraindicated in patients with severe renal impairment (creatinine clearance of ≤30 mL/min) [see Dosage and Administration (2.1), Warnings and Precautions (5.1), Use in Specific Populations (8.6), and Clinical Pharmacology (12.3)].

What is Campral?

Campral (acamprosate) affects chemicals in the brain that may be unbalanced in a person who is addicted to alcohol. Acamprosate works by restoring this chemical balance in the brain in an alcohol-dependent person who has recently quit drinking.

Campral is used together with behavior modification and counseling support to help a person who has recently quit drinking alcohol continue to choose not to drink.

Campral is not likely to be helpful if you have not already quit drinking or undergone detoxification. It may not help you if you are also addicted to other substances besides alcohol.

Campral may also be used for purposes not listed in this medication guide.

How should I take Campral?

Take Campral exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Start taking Campral as soon as possible after you have quit drinking.

You may take Campral with or without food.

Do not crush, chew, or break a delayed-release tablet. Swallow the tablet whole.

Take this medication for the full prescribed length of time, even if you relapse and drink alcohol. While you are taking Campral, tell your doctor about any alcoholic drinks you consume, no matter how many.

Use this medicine regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.

Campral is only part of a complete program of treatment that also includes counseling support and continued abstinence from alcohol.

Store at room temperature away from moisture and heat.

What should I avoid while taking Campral?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

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