Methscopolamine

Name: Methscopolamine

If OVERDOSE is suspected

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Pronunciation

(meth skoe POL a meen)

Index Terms

  • Methscopolamine Bromide

Dosing Geriatric

Refer to adult dosing.

Dietary Considerations

Take 30 minutes before meals and at bedtime.

Storage

Store at 15°C to 30° C (59° F to 86° F).

Adverse Reactions

Frequency not defined.

Cardiovascular: Palpitation, tachycardia

Central nervous system: Headache, insomnia, flushing, nervousness, drowsiness, dizziness, confusion, fever, CNS stimulation may be produced with large doses

Dermatologic: Dry skin, urticaria

Endocrine & metabolic: Lactation suppressed

Gastrointestinal: Constipation, xerostomia, dry throat, dysphagia, nausea, vomiting, loss of taste

Genitourinary: Impotence, urinary hesitancy, urinary retention

Neuromuscular & skeletal: Weakness

Ocular: Blurred vision, cycloplegia, ocular tension increased, pupil dilation

Respiratory: Dry nose

Miscellaneous: Allergic reaction, diaphoresis decreased, hypersensitivity reactions, anaphylaxis

Pregnancy Risk Factor C Pregnancy Considerations

Animal reproduction studies have not been conducted. Methscopolamine is a derivative of scopolamine. Scopolamine is reported to cross the placenta; fetal toxicity noted in case reports.

Interactions

Consult your pharmacist.

Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

Does Methscopolamine Powder interact with other medications?

Precautions

Methscopolamine is contraindicated in patients with glaucoma, obstructive uropathy, obstructive disease of the gastrointestinal tract, paralytic ileus, intestinal atony of the elderly or debilitated patient, unstable cardiovascular status in acute hemorrhage, severe ulcerative colitis, toxic megacolon complicating ulcerative colitis, and myasthenia gravis.

Because gastrointestinal antispasmodics are highly anticholinergic drugs, methscopolamine meets Beers criteria as a medication that is potentially inappropriate for use in older adults.

With overdose, a curare-like action may occur, characterized by muscular weakness and possible paralysis.

Safety and effectiveness have not been established in pediatric patients (less than 18 years of age).

Dialysis

Data not available

Methscopolamine Pregnancy Warnings

Methscopolamine has been assigned to pregnancy category C by the FDA. Animal studies have not been reported. There are no controlled data in human pregnancy. Methscopolamine is only recommended for use during pregnancy when benefit outweighs risk.

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