Mirvaso topical

Name: Mirvaso topical


  • Relatively selective α2-adrenergic agonist.1 2 5 6

  • Topical application appears to reduce erythema through direct vasoconstriction.1 2 5 6

  • May act by targeting α-adrenergic receptors present in the smooth muscle sheath encasing the vessel wall of superficial cutaneous blood vessels.5

Advice to Patients

  • Patients should be given a copy of the patient information provided by the manufacturer.1

  • Importance of advising patients that brimonidine gel should only be used as directed by a clinician.1

  • Importance of advising patients that brimonidine gel is for external use only and that contact with the eyes and lips should be avoided; importance of not using the drug orally or intravaginally.1

  • Importance of advising patients not to apply to irritated skin or open wounds.1

  • Importance of washing hands immediately after applying brimonidine gel.1

  • Importance of advising patients of the possibility of erythema or flushing.1

  • Importance of advising patients to report adverse reactions to a clinician.1

  • Importance of advising patients to keep brimonidine gel out of the reach of children.1 (See Serious Adverse Reactions Following Ingestion under Cautions.)

  • Importance of women informing clinicians if they are or plan to become pregnant or plan to breast-feed.1

  • Importance of informing clinicians of existing or contemplated concomitant therapy, including prescription and OTC drugs, as well as any concomitant illnesses.1

  • Importance of informing patients of other important precautionary information.1 (See Cautions.)


Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Avoid the use of skin care products that can cause further irritation (such as cleaners that contain alcohol, tinctures, astringents, abrasives, and peeling agents). Consult your doctor or pharmacist for details.