Phytomenadione injection

Name: Phytomenadione injection

About phytomenadione

Type of medicineA form of vitamin K
Used forBleeding caused by anticoagulant medicines; to reverse the anticoagulant effects of warfarin before an operation
Also calledPhytonadione (in US); Konakion® MM
Available asInjection for intravenous or oral use

Vitamin K is a fat-soluble vitamin which is essential for blood clotting. It also plays a role in bone health.

People who take anticoagulant medicines such as warfarin are at risk of bleeding. Regular blood tests are needed to check on how quickly the blood clots. The aim is to get the dose of warfarin just right so that the blood does not clot as easily as normal, but not so much as to cause bleeding problems. If the dose of the anticoagulant is too high then bleeding can become a problem. Phytomenadione is given as an antidote to bleeding caused by anticoagulant medicines such as warfarin. It is likely to be given by injection in hospital.

If a person who is taking a medicine like warfarin needs to have an operation at short notice then the effects of the anticoagulant medicine will need to be reversed before the surgery takes place. Vitamin K is given to reduce the risk of bleeding during the surgery.

Before having phytomenadione

To make sure that this is the right treatment for you it is important that your doctor knows:

  • If you are pregnant or breast-feeding.
  • If you are taking or using any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.
  • If you have ever had an allergic reaction to a medicine.

How phytomenadione is given

  • Phytomenadione injection will be given by a doctor or nurse. Ask to read the manufacturer's printed information leaflet from inside the pack - it will give you more information about treatment with phytomenadione.
  • You may be given the injection to swallow by mouth. This is often the case for people who are taking phytomenadione before surgery, or who have abnormal blood results but who do not have any symptoms of bleeding.

Getting the most from your treatment

  • If you have any questions about your treatment, please ask your doctor or nurse for further advice.
  • After you have left hospital, remember to keep your regular clinic appointments so that your progress can be monitored.

Can phytomenadione cause problems?

Very occasionally there have been reports of irritation or allergic-type reactions, but otherwise the medicine is unlikely to cause side-effects. If you experience any other symptoms which you think could be due to phytomenadione, please speak with your doctor or pharmacist for further advice.