Name: Ravulizumab-cwvz Injection
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Why is this medication prescribed?
Ravulizumab-cwvz injection is used to treat paroxysmal nocturnal hemoglobinuria (PNH: a type of anemia in which too many red blood cells are broken down in the body, so there are not enough healthy cells to bring oxygen to all parts of the body). Ravulizumab-cwvz is in a class of medications called monoclonal antibodies. It works by blocking the activity of the part of the immune system that may damage blood cells.
What special precautions should I follow?
Before receiving ravulizumab-cwvz injection,
- tell your doctor and pharmacist if you are allergic to ravulizumab-cwvz, any other medications, or any of the ingredients in ravulizumab-cwvz injection. Ask your pharmacist or check the Medication Guide for a list of the ingredients.
- tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
- tell your doctor if you have or have ever had high cholesterol levels.
- tell your doctor if you are pregnant or plan to become pregnant. If you become pregnant while receiving ravulizumab-cwvz injection, call your doctor.
- tell your doctor if you are breastfeeding. You should not breastfeed while you are receiving ravulizumab-cwvz and for 8 months after your final treatment dose.
What side effects can this medication cause?
Ravulizumab-cwvz may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- joint pain
Some side effects can be serious. If you experience any of these symptoms or those listed in the IMPORTANT WARNING or HOW sections, call your doctor immediately or get emergency medical treatment:
- extreme tiredness, blood in urine, stomach pain, difficulty swallowing, or an inability to get or keep an erection (during treatment and for 16 weeks after your final treatment dose)
- pain, swelling, warmth, redness, or tenderness in one leg only; slow or difficult speech; weakness or numbness of an arm or leg; or shortness of breath (during treatment and for 16 weeks after your final treatment dose)
Ravulizumab-cwvz may cause other side effects. Call your doctor if you have any unusual problems while receiving this medication.
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).
In case of emergency/overdose
In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.