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Amplification of the vasodilatory effects of Transderm-Nitro by sildenafil may result in severe hypotension. The time course and dose dependence of this interaction have not been studied. Appropriate supportive care has not been studied, but it seems reasonable to treat this as a nitrate overdose, with elevation of the extremities and with central volume expansion.
The benefits of transdermal nitroglycerin in patients with acute myocardial infarction or congestive heart failure have not been established. If one elects to use nitroglycerin in these conditions, careful clinical or hemodynamic monitoring must be used to avoid the hazards of hypotension and tachycardia.
A cardioverter/defibrillator should not be discharged through a paddle electrode that overlies a Transderm-Nitro patch. The arcing that may be seen in this situation is harmless in itself, but it may be associated with local current concentration that can cause damage to the paddles and burns to the patient.
What is the most important information i should know about nitroglycerin transdermal (minitran, nitrek, nitro td patch-a, nitro-dur)?
You should not use this medication if you are allergic to nitroglycerin, isosorbide mononitrate (Imdur), or isosorbide dinitrate (BiDil, Isordil).
Before using nitroglycerin transdermal, tell your doctor if you have congestive heart failure, low blood pressure, glaucoma, anemia, or a history of heart attack, stroke, or head injury.
Do not use this medication to treat an angina attack that has already begun. It will not work fast enough.
Nitroglycerin transdermal can cause severe headaches, especially when you first start using it. Do not stop using the skin patches, and ask your doctor before using any headache pain medication.
Nitroglycerin may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
Call your doctor at once if you have a serious side effect such as worsening chest pain, pain spreading to the arm or shoulder, nausea, vomiting, sweating, blurred vision and dry mouth, or fainting.
Drinking alcohol can increase certain side effects of nitroglycerin.
The nitroglycerin transdermal patch may burn your skin if you wear the patch during an MRI (magnetic resonance imaging). Remove the patch before undergoing such a test.
What happens if i miss a dose (minitran, nitrek, nitro td patch-a, nitro-dur)?
Apply a patch as soon as you remember, and keep it on for the rest of your wearing time without changing your patch removal schedule. If you miss a dose and it is almost time to apply your next patch, wait until then to apply the patch and skip the missed dose.
Do not use extra patches to make up a missed dose.
Uses of Transderm-Nitro
Nitroglycerin is a prescription medicine used to treat and prevent angina associated with coronary artery disease (CAD).
This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.
Transderm-Nitro Drug Class
Transderm-Nitro is part of the drug classes:
Antihemmorhoidal Muscle Relaxants
Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your doctor if you take:
- any medicines that are used to treat angina, heart failure, or an irregular heartbeat.
- any medicines that reduce blood pressure.
- any diuretics (water pills).
- medications to treat depression or psychiatric illness.
- ergotamine or similar drugs for migraine headaches.
- the blood thinner medicine heparin.
- any medicines for erectile dysfunction.
Do not consume alcohol while taking nitroglycerin, as this can lower your blood pressure.
This is not a complete list of nitroglycerin drug interactions. Ask your doctor or pharmacist for more information.
Transderm-Nitro Food Interactions
Medications can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of nitroglycerin, there are no specific foods that you must exclude from your diet when receiving this medication.
Transderm-Nitro and Lactation
Tell your doctor if you are breastfeeding. It is not known if nitroglycerin is excreted in human breast milk or if it will harm your nursing baby.
- Do not chew, crush, or swallow nitroglycerin tablets.
- You should sit down when taking nitroglycerin tablets and use caution when you stand up. This eliminates the possibility of falling due to lightheadedness or dizziness.
- One tablet should be dissolved under the tongue or in the oral cavity at the first sign of chest pain.
- The dose may be repeated approximately every 5 minutes, until the chest pain is relieved.
- If the pain persists after a total of 3 tablets in a 15-minute period, or is different than you typically experience, call your doctor or seek emergency help.
- Nitroglycerin may be used 5 to 10 minutes prior to activities that might cause chest pain.
- You may feel a burning or tingling sensation in your mouth when you take nitroglycerin.
- Do not breastfeed. It is not known if nitroglycerin will pass through your milk.
- Do not consume alcohol while taking nitroglycerin, as this can lower your blood pressure.
- Do not start any new prescription or non-prescription medicines or supplements, unless you check with your doctor first.
Uses For Transderm-Nitro
Nitroglycerin ointment or skin patch is used to prevent angina (chest pain) caused by coronary artery disease. It does not work fast enough to relieve the pain of an angina attack that has already started.
Nitroglycerin belongs to the group of medicines called nitrates. It works by relaxing the blood vessels and increasing the supply of blood and oxygen to the heart while reducing its work load. When used regularly on a long-term basis, this helps prevent angina attacks from occurring.
This medicine is available only with your doctor's prescription.