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How should this medicine be used?
Clorazepate comes as a tablet to take by mouth. It is usually taken one to three times a day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take clorazepate exactly as directed.
If you are taking clorazepate to treat anxiety or seizures, your doctor will probably start you on a low dose of clorazepate and gradually increase your dose. If you are taking clorazepate to treat alcohol withdrawal, your doctor will probably start you on a high dose of clorazepate and gradually decrease your dose as your symptoms are controlled.
Clorazepate can be habit-forming. Take clorazepate exactly as directed. Do not take a larger dose, take it more often, or take it for a longer time than prescribed by your doctor.
Clorazepate may help to control seizures and anxiety, but it will not cure these conditions. Continue to take clorazepate even if you feel well. Do not stop taking clorazepate without talking to your doctor. Your doctor will probably decrease your dose gradually. If you suddenly stop taking clorazepate, you may experience withdrawal symptoms such as nervousness, difficulty falling asleep or staying asleep, irritability, diarrhea, muscle aches, memory problems, seizures, confusion, uncontrollable shaking of a part of the body, stomach cramps, muscle cramps, vomiting, or sweating.
Other uses for this medicine
This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.
What special dietary instructions should I follow?
Unless your doctor tells you otherwise, continue your normal diet.
Chemically, TRANXENE is a benzodiazepine. The empirical formula is C16H11ClK2N2O4; the molecular weight is 408.92; 1H-1, 4-Benzodiazepine-3-carboxylic acid, 7-chloro-2,3-dihydro-2-oxo-5-phenyl-, potassium salt compound with potassium hydroxide (1:1) and the structural formula may be represented as follows:
The compound occurs as a fine, light yellow, practically odorless powder. It is insoluble in the common organic solvents, but very soluble in water. Aqueous solutions are unstable, clear, light yellow, and alkaline.
TRANXENE T-TAB tablets contain either 3.75 mg, 7.5 mg or 15 mg of clorazepate dipotassium for oral administration.
Inactive ingredients for TRANXENE T-TAB Tablets: Colloidal silicon dioxide, FD&C Blue No. 2 (3.75 mg only), FD&C Yellow No. 6 (7.5 mg only), FD&C Red No. 3 (15 mg only), magnesium oxide, magnesium stearate, microcrystalline cellulose, potassium carbonate, potassium chloride, and talc.
TRANXENE 3.75 mg scored T-TAB tablets are supplied as blue-colored tablets bearing the letters OV, the distinctive T shape and a two-digit designation, 31: Bottles of 100 (NDC 55292-301-01).
7.5 mg scored T-TAB tablets are supplied as peach-colored tablets bearing the letters OV, the distinctive T shape and a two-digit designation, 32: Bottles of 100 (NDC 55292-302-01).
15 mg scored T-TAB tablets are supplied as lavender-colored tablets bearing the letters OV, the distinctive T shape and a two-digit designation, 33: Bottles of 100 (NDC 55292-303-01).
Recommended storage: Protect from moisture. Keep bottle tightly closed. Store at 20-25°C (68-77°F). See USP controlled room temperature. Dispense in a USP tight, light-resistant container.
Manufactured by: AbbVie LTD, Barceloneta, PR 00617. For: Recordati Rare Diseases Inc., Lebanon, NJ 08833, U.S.A. Revised: February 2013.
What should i discuss with my healthcare provider before taking clorazepate (tranxene sd, tranxene t-tab)?
Do not use this medication if you have narrow-angle glaucoma, or if you are allergic to clorazepate or to other benzodiazepines, such as alprazolam (Xanax), chlordiazepoxide (Librium), diazepam (Valium), lorazepam (Ativan), or oxazepam (Serax).
Before taking clorazepate, tell your doctor if you are allergic to any drugs, or if you have:
- asthma, emphysema, bronchitis, chronic obstructive pulmonary disorder (COPD), or other breathing problems;
- kidney or liver disease;
- epilepsy or other seizure disorder;
- a history of depression or suicidal thoughts or behavior; or
- a history of drug or alcohol addiction.
If you have any of these conditions, you may need a dose adjustment or special tests during treatment.
Clorazepate can cause birth defects in an unborn baby. Do not use clorazepate without your doctor's consent if you are pregnant. Tell your doctor if you become pregnant during treatment. Use an effective form of birth control while you are using this medication.
Clorazepate can pass into breast milk and could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
The sedative effects of clorazepate may last longer in older adults. Accidental falls are common in elderly patients who take benzodiazepines. Use caution to avoid falling or accidental injury while you are taking clorazepate.
Do not give this medication to a child younger than 9 years old.
Where can i get more information?
Your pharmacist can provide more information about clorazepate.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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- Panic Attacks
- Prescription Anxiety Medications
- Seizure (Epilepsy)
Tranxene is a prescription medication used to treat anxiety and seizures. Tranxene belongs to a group of drugs called benzodiazepines. These work by reducing abnormal electrical activity in the brain.
This medication comes in tablet form and is taken 1 to 3 times a day, with or without food.
Common side effects of Tranxene include upset stomach, drowsiness, and dizziness. Do not drive or operate heavy machinery until you know how Tranxene affects you.